Bio-Sponge™, the commercially available Di-Tri-Octahedral smectite product from Platinum Performance Inc., bound 99% of Clostridium difficile toxins A and B and Clostridium perfringens enterotoxins in one in vitro study and effectively neutralized Clostridium toxins in another study.

Di-Tri-Octahedral Smectite for use in Post-Operative Diarrhea in Equids with Surgical Disease of the Large Intestine: Results of a randomized clinical trial. Diana Hassel, DVM, PhD, Phoebe Smith, DVM, Jorge Nieto, DVM, Pablo Beldomenico, and Sharon J. Spier, DVM, PhD, University of California, Davis, 2009.

by Diana Hassel a Sharon Spier. The aim of this study was to evaluate the effects of a commercially available di-tri-octahedral Comprised of a natural clay, Di-Tri-Octahedral Smectite A negatively charged intestinal adsorbant designed to help support healthy intestinal function Widely used to support healthy gastrointestinal function in foals.Newborn foals: For best results, following an adequate intake of colostrum administer 30cc of Bio-Sponge® Paste 6 hours after the foal first nurses the mare. CONICET Digital, el repositorio institucional del CONICET, un servicio gratuito para acceder a la producción científico-tecnológica de investigadores, becarios y demás personal del CONICET. Which drugs to choose — POLYSORB or smectite For many years in every human body accumulate many harmful substances. Poor diet, sedentary lifestyle, stress – all this contributes to the fact that over time, the body becomes clogged with unnecessary substances and overall health getting worse. For this reason, exacerbated many chronic diseases.

Di tri octahedral smectite

Surgical and Radiological Sciences. Smectite is defined in clay mineralogy as a 2:1 clay - consisting of an octahedral sheet sandwiched between two tetrahedral sheets. Smectites may swell by the uptake of water in the clay (Di-tri-octahedral Smectite min. 70%) GMP+ & FSA geborgd: Gebruiksaanwijzing: Gezonde pasgeboren veulens: Na een adequate inname van biest verstrek 1 volle maatschep (25 gram) DiaTox Absorber poeder, gemixt met 30 ml water, toedienen. Toedienen 6 uur nadat het veulen de eerste voeding van de merrie binnen heeft gekregen.

Research performed in adult horses and foals, as well as through in vitro trials, indicates that Bio-Sponge® (Di-Tri Octahedral (DTO) smectite) is an effective tool for a variety of health concerns that result in diarrhea or gastrointestinal disturbances.

Nutritional support. Total or partial parenteral (TPN, PPN) nutrition should be considered in neonates. However, treatment with Bio-sponge® paste, which is composed of a natural clay called Di-Tri-Octahedral Smectite, has been shown in several studies to be effective at adsorption of harmful toxins in the equine GI tract (4) and is what we use most often when treatment for foal heat diarrhea is … Di-tri-octahedral smectite for the prevention of post-operative diarrhea in equids with surgical disease of the large intestine: results of a randomized clinical trial. Vet J. 2009; 182(2):210-4 (ISSN: 1532-2971) Biosponge: Di-tri-octahedral (DTO) smectite (clay minerals) is a natural hydrated aluminomagnesium silicate that binds to digestive mucus and increases resistance to bacterial damage by absorbing Article Unit Active component; Bio Sponge platinum: 9500 gr: Di-Tri-Octahedral Smectite: Equi-Sumo AP: 1000 ml: Ricebran oil, Herbs, Gamma-Orizanol: Quietex Paste Syringe Oral di-tri-octahedral smectite (Biosponge), 500 mg/kg BW, QID was administered for 3 d, and nasoesophageal feeding frequency was reduced.

Includes the active ingredient Di-Tri-Octahedral Smectite. This highly effective intestinal support supplement works rapidly to correct diarrhea. Available in powder

Di‐tri‐octahedral smectite is a type of clay that adsorbs C. difficile toxins in vitro, 28 and is commonly used in the treatment of CDI in horses. Probiotic therapy has been evaluated in humans with CDI. Results have been somewhat conflicting and equivocal, however, Conclusions and Clinical Relevance—Di-tri-octahedral smectite effectively adsorbed C perfringens exotoxins in vitro and had a dose-dependent effect on the availability of equine colostral antibodies.

PubMed Article CAS Google Scholar 34. METHODS: Substances commonly used in equine practice (activated charcoal composition, di-tri-octahedral smectite, mineral oil and activated charcoal) were tested for their binding capacity for HGA using an in vitro incubation method.

Sixty-seven horses with surgical disease of the large intestine were randomly assigned to be "Di-tri-octahedral smectite was effective in neutralizing Clostridium difﬁcile toxins A and B as well as Clostridium perfringens enterotoxin in vitro.
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Di-Tri-Octahedral Smectite for use in Post-Operative Diarrhea in Equids with Surgical Disease of the Large Intestine: Results of a randomized clinical trial. Diana Hassel, DVM, PhD, Phoebe Smith, DVM, Jorge Nieto, DVM, Pablo Beldomenico, and Sharon J. Spier, DVM, PhD, University of California, Davis, 2009.

It contains di-tri-octahedral smectite, a unique Kelley Neelley, DVM, and Doug Herthel, DVM, Alamo Pintado Equine Medical Center, 2000. 2003. Evaluation of in vitro Properties of Di-Tri-Octahedral Smectite Includes the active ingredient Di-Tri-Octahedral Smectite.

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Di-tri-octahedral smectite 5 (DTOS) is a hydrated, negatively charged alumina-magnesium silicate which attracts and binds positively charged bacterial exo-and endotoxins, such as C. difficile

Sixty-seven horses with surgical disease of the large intestine were randomly assigned to be treated with DTO smectite (n=37; 0.5 kg via nasogastric Abstract. The minerals of the montmorillonite group (smectites) can be distinguished from the vermiculites, as they are very similar to them in their thermal behaviour, as regards the temperatures of the exothermic peak.